abstract：PURPOSE OF REVIEW:Infective endocarditis continues to pose major challenges in diagnosis and management despite advances in understanding the epidemiology, microbiology, and pathology of the disease. The purpose of this article is to provide a review of diagnosis, microbiology, and treatment of infective endocarditis, ...

journal_title：Current opinion in cardiology

authors： Devlin RK,Andrews MM,von Reyn CF

更新日期：2004-03-01 00:00:00

abstract：PURPOSE OF REVIEW:This review describes changes in indications for implantable cardioverter-defibrillator (ICD) implantation made in the American College of Cardiology, American Heart Association, and North American Society of Pacing and Electrophysiology 2002 update of the 1998 guideline for the implantation of cardia...

journal_title：Current opinion in cardiology

authors： Epstein AE

更新日期：2004-01-01 00:00:00

abstract：PURPOSE OF REVIEW:Diagnostic testing using noninvasive imaging has become an integral part of risk stratification in patients with coronary artery disease. It is important to understand the integral strengths and weaknesses between the different modalities of stress testing and to apply accurately the type of test the ...

journal_title：Current opinion in cardiology

authors： Maganti K,Rigolin VH

更新日期：2003-11-01 00:00:00

abstract：:In addition to necrosis, apoptosis makes a significant contribution to cell death following acute myocardial ischemia; apoptosis is particularly enhanced during reperfusion. Several studies are beginning to indicate that the cell death by apoptosis may be preventable. A boost in the research in this direction has been...

journal_title：Current opinion in cardiology

authors： Garg S,Hofstra L,Reutelingsperger C,Narula J

更新日期：2003-09-01 00:00:00

abstract：:Recent evidence indicates that infections or a pathogen burden contribute to the development and progression of atherosclerosis. While the mechanism of infection contributing to the pathogenesis is not fully elucidated, I hypothesize that heat shock proteins may be a link between infections and atherosclerosis. Heat s...

journal_title：Current opinion in cardiology

authors： Xu Q

更新日期：2003-07-01 00:00:00

abstract：:A growing number of patients present with heart failure. Some of them may qualify for surgical correction of their cardiac condition. Since heart transplantation will always be available to only a small number of patients, several new surgical techniques have been developed for approval in heart failure patients. Clas...

journal_title：Current opinion in cardiology

authors： Loebe M,Soltero E,Thohan V,Lafuente JA,Noon GP

更新日期：2003-05-01 00:00:00

abstract：:A trend toward use of less invasive, nonsurgical approaches to the treatment of congenital heart disease has developed. Although transcatheter valve replacements and ventricular septal defect closures have already been performed in children, many other techniques and devices are being developed for the palliation of c...

journal_title：Current opinion in cardiology

authors： Levi DS,Alejos JC,Moore JW

更新日期：2003-03-01 00:00:00

abstract：:Assessment of the pulmonary circulation and right ventricular function is a cornerstone in the evaluation of the patient as a potential heart transplant recipient. The importance of pulmonary hypertension is linked to outcomes in the posttransplant period. Preoperative pulmonary vascular resistance is an independent r...

journal_title：Current opinion in cardiology

authors： Natale ME,Piña IL

更新日期：2003-03-01 00:00:00

abstract：:Several investigators have identified the pulmonary vein as the most common initiator of atrial fibrillation, and isolation of the pulmonary vein from atrial tissue can cure approximately 70% of patients with paroxysmal atrial fibrillation. Ongoing trials of a new device may increase the success rate and decrease the ...

journal_title：Current opinion in cardiology

authors： Tsai CF,Tai CT,Chen SA

更新日期：2003-01-01 00:00:00

abstract：:The authors analyzed the early outcomes in two groups of patients undergoing coronary artery bypass grafting (CABG) with single versus bilateral internal thoracic arteries (ITA) in their institution. One thousand sixty-nine patients underwent CABG with single or bilateral ITAs from 1990 to 2000. Of these patients, 911...

journal_title：Current opinion in cardiology

authors： Walkes JC,Earle N,Reardon MJ,Glaeser DH,Wall MJ Jr,Huh J,Jones JW,Soltero ER

更新日期：2002-11-01 00:00:00

abstract：:A faster and more precise method for determining hibernating myocardium remains the holy grail of noninvasive cardiac imaging. Nuclear or echocardiogram-based imaging techniques have been the key modalities for evaluating important markers of cardiac viability. Advances in hardware and software for cardiac magnetic re...

journal_title：Current opinion in cardiology

authors： Poon M,Fuster V,Fayad Z

更新日期：2002-11-01 00:00:00

abstract：:Myocardial contrast echocardiography (MCE) is an emerging technique in which microbubble contrast agents are visualized in the coronary microvasculature. MCE is an ideal modality for the noninvasive evaluation of acute coronary syndromes because it provides portable, simultaneous assessment of regional wall motion and...

journal_title：Current opinion in cardiology

authors： Ward RP,Lang RM

更新日期：2002-09-01 00:00:00

abstract：:Increased carotid intima media thickness (IMT) is relatively simple, inexpensive, and reproducible noninvasive marker of global atherosclerotic disease. It is a frequently used experimental tool in epidemiologic studies to identify and follow cardiovascular disease. There is evidence that early detection of atheroscle...

journal_title：Current opinion in cardiology

authors： Sinha AK,Eigenbrodt M,Mehta JL

更新日期：2002-09-01 00:00:00

abstract：:The human race is genetically programmed to consume less than 1 g of salt per day. In most human populations, the diet contains 6 to 12 g of salt per day and, in contrast to populations that consume less than 3 g of salt per day, their blood pressure rises with age. Independent of the rise in blood pressure, a high-sa...

journal_title：Current opinion in cardiology

authors： De Wardener HE,MacGregor GA

更新日期：2002-07-01 00:00:00

abstract：:Pathogenesis of familial inherited arrhythmias is being progressively clarified thanks to the insights provided by molecular biology and by functional studies. Transmembrane or intracellular ion channel mutations have been identified in genetically determined forms of polymorphic ventricular tachycardia and sudden dea...

journal_title：Current opinion in cardiology

authors： Napolitano C,Priori SG

更新日期：2002-05-01 00:00:00

abstract：:The publications of 2000 and 2001 stress how interventional pediatric cardiology has moved from angioplasty to device placement. This review summarizes the important articles during the past year that evaluated the safety and efficacy of atrial septal defect devices, patent ductus occluders, and stents to treat coarct...

journal_title：Current opinion in cardiology

authors： Rocchini AP

更新日期：2002-05-01 00:00:00

abstract：:Implantable cardioverter defibrillators (ICDs) have become an important therapeutic modality for patients who have had a cardiac arrest or are at risk for life-threatening ventricular arrhythmias. Clinical trials have confirmed the role of the ICD for patients with sustained ventricular arrhythmias and have expanded t...

journal_title：Current opinion in cardiology

authors： Swygman C,Wang PJ,Link MS,Homoud MK,Estes NA 3rd

更新日期：2002-01-01 00:00:00

abstract：:With 550,000 new cases each year, congestive heart failure is a major medical problem. Several medical therapies, including digoxin, angiotensin-converting enzyme inhibitors, and beta-blockers, have reduced the number of re-hospitalizations and slowed the progression of congestive heart failure. Angiotensin-converting...

journal_title：Current opinion in cardiology

authors： Luck JC,Wolbrette DL,Boehmer JP,Ulsh PJ,Silber D,Naccarelli GV

更新日期：2002-01-01 00:00:00

abstract：:The presence, and in many cases the regulated synthesis, of components of the renin-angiotensin system have been demonstrated in multiple tissues, indicating the existence of tissue angiotensin-generating systems. These vary with respect to which renin-angiotensin system components are synthesized locally and which ar...

journal_title：Current opinion in cardiology

authors： Re RN

更新日期：2001-11-01 00:00:00

abstract：:Optimized medical treatment for the non-ST segment elevation acute coronary syndromes (NSTE ACS) should consist of a combined antithrombotic/anti-anginal regimen. Standard antithrombotic treatment is currently unfractionated heparin and aspirin, and in high-risk patients glycoprotein IIb/IIIa inhibitors. However, low-...

journal_title：Current opinion in cardiology

authors： Cohen M

更新日期：2001-11-01 00:00:00

abstract：:For more than three decades, conventional coronary artery bypass grafting (full sternotomy, cardiopulmonary bypass, and cardioplegic arrest) has been the treatment of choice for patients with multi-vessel coronary artery disease. However, neurologic injury secondary to ascending aortic manipulation and systemic inflam...

journal_title：Current opinion in cardiology

authors： Filsoufi F,Aklog L,Adams DH

更新日期：2001-09-01 00:00:00

abstract：:Pulmonary edema is one of the most serious and life-threatening situations in emergency medicine. Lately it has become apparent that in most cases pulmonary edema is not caused by fluid accumulation but rather fluid redistribution that is directed into the lungs because of heart failure. Based on a series of recently ...

journal_title：Current opinion in cardiology

authors： Cotter G,Kaluski E,Moshkovitz Y,Milovanov O,Krakover R,Vered Z

更新日期：2001-05-01 00:00:00

abstract：:The COCPIT study, performed in a complete national cohort of adult patients consecutively listed for cardiac transplantation in Germany in 1997, found a beneficial effect only in the group that was at high risk of dying from heart failure without transplantation. If these results can be reproduced in other countries, ...

journal_title：Current opinion in cardiology

authors： Deng MC,Smits JM,De Meester J,Hummel M,Schoendube F,Scheld HH

更新日期：2001-03-01 00:00:00

abstract：:Recent data have emerged to help guide the use of implantable pacemakers and implantable defibrillators in patients who have hypertrophic cardiomyopathy (HCM). Controlled studies of the use of dual chamber pacemakers to treat outflow tract obstruction in HCM have shown little benefit, and have raised the possibility t...

journal_title：Current opinion in cardiology

authors： Freedman RA

更新日期：2001-01-01 00:00:00

abstract：:With marked improvements in stent technology as adjunct to balloon angioplasty for multivessel coronary disease, several newer trials are currently in progress reviewing the optimal revascularization strategy. This review provides background from older studies and addresses the current progress and design of these new...

journal_title：Current opinion in cardiology

authors： Bakhai A,Stables RH,Prasad S,Sigwart U

更新日期：2000-11-01 00:00:00

abstract：:Because the main cause of death in patients with established coronary heart disease (CHD) is sudden cardiac death (SCD), physicians should develop specific strategy, including dietary changes, to prevent it. In the long term, reduction of the diet-dependent chronic risk factors of CHD, hypercholesterolemia, hypertensi...

journal_title：Current opinion in cardiology

authors： de Lorgeril M,Salen P

更新日期：2000-09-01 00:00:00

abstract：:The normal myocardium is composed of a variety of cells: cardiac myocytes and noncardiomyocytes, which include endothelial and vascular smooth muscle cells and fibroblasts. Hypertensive heart disease involves a structural remodeling of muscular and nonmuscular compartments. It is not the quantity but rather the qualit...

journal_title：Current opinion in cardiology

authors： Weber KT

更新日期：2000-07-01 00:00:00

abstract：:Evaluation of the hemodynamic response in heart failure is a useful adjunct in clinical management. Invasive monitoring has been the accepted gold standard of hemodynamic assessment but carries with it significant associated risks. Noninvasive hemodynamic assessment in heart failure previously has been either unreliab...

journal_title：Current opinion in cardiology

authors： Rosenberg P,Yancy CW

更新日期：2000-05-01 00:00:00

abstract：:Primary cardiac tumors are rare clinical entities. Benign tumors are often amenable to surgical excision, whereas malignant tumors are seldom resectable. The literature has reported that 28 patients have undergone orthotopic heart transplantation for inoperable primary cardiac tumors. The results of these transplants ...

journal_title：Current opinion in cardiology

authors： Gowdamarajan A,Michler RE

更新日期：2000-03-01 00:00:00

abstract：:In the past 2 years, significant advances have been made in class III antiarrhythmic drug therapy. In patients with ventricular arrhythmias and implantable cardioverter defibrillators (ICDs), antiarrhythmic agents are increasingly being used as adjunct therapy to decrease the frequency of ICD discharges. Sotalol was r...

journal_title：Current opinion in cardiology

authors： Sager PT

更新日期：2000-01-01 00:00:00

abstract：:The focus of this review is the advantages of simultaneously assessing myocardial perfusion and left ventricular function. Nuclear cardiology imaging techniques as well as the development of technetium-labeled perfusion tracers now permit combined myocardial-perfusion and left-ventricular function studies at a single ...

journal_title：Current opinion in cardiology

authors： Borges-Neto S,Shaw LK

更新日期：1999-11-01 00:00:00

abstract：:Angiogenesis, the de novo formation of new vasculature, is a critical response to ischemia that provides neovascularization of ischemic tissues. In therapeutic angiogenesis, an angiogen--a mediator that induces angiogenesis--is delivered to targeted tissues, augmenting the native angiogenic process and enhancing reper...

journal_title：Current opinion in cardiology

authors： Hamawy AH,Lee LY,Crystal RG,Rosengart TK

更新日期：1999-11-01 00:00:00

abstract：:Over the past year, significant new advances have been made in preventive cardiology. New trials of lipid lowering, estrogen therapy, and hypertension control have added to our understanding of the pathophysiology and prevention of coronary atherosclerosis. This review highlights these new trials and provides insight ...

journal_title：Current opinion in cardiology

authors： Foody JA

更新日期：1999-09-01 00:00:00

abstract：:Acute mesenteric ischemia (AMI) remains a complex and difficult clinical problem. Such acute ischemia is usually either embolic or thrombotic in nature, but other etiologies exist. The diagnosis of AMI is difficult to establish and often delayed, resulting in irreversible bowel injury that requires intestinal resectio...

journal_title：Current opinion in cardiology

authors： Vicente DC,Kazmers A

更新日期：1999-09-01 00:00:00

abstract：:Currently 14 million individuals in the United States have coronary disease. Within the next 2 decades, this number is expected to increase to 21 million persons. To minimize the excessive risk of recurrent cardiac events in these people, evidence-based, cost-effective prevention strategies must be developed. This rev...

journal_title：Current opinion in cardiology

authors： Blazing MA,O'Connor CM

更新日期：1999-07-01 00:00:00

abstract：:Ventricular remodeling refers to changes in ventricular geometry, volume, mass, and myocellular structure in response to myocardial injury or alteration in loading conditions. Although initially adaptive as a consequence of the initial damage to the myocardium, progressive ventricular remodeling is ultimately a malada...

journal_title：Current opinion in cardiology

authors： Bozkurt B

更新日期：1999-05-01 00:00:00

abstract：:Brugada syndrome is characterized by ST segment elevation in the right precordial leads, V1-V3 (unrelated to ischemia or structural disease), normal QT intervals, apparent right bundle branch block, and sudden cardiac death, particularly in men of Asian origin. An autosomal dominant mode of inheritance with variable e...

journal_title：Current opinion in cardiology

authors： Antzelevitch C

更新日期：1999-05-01 00:00:00

abstract：:This review describes to date the experience with combined heart-kidney transplant (HNTx) from a single donor. HNTxs are very uncommon relative to single-organ transplants of the heart and kidney, as well as combined kidney-pancreas and combined kidney-liver transplants. Two groups of patients seem to be candidates fo...

journal_title：Current opinion in cardiology

authors： Castillo-Lugo JA,Brinker KR

更新日期：1999-03-01 00:00:00

abstract：:Minimally invasive cardiac surgery has evolved in response to the intrinsic irony facing cardiac surgeons: that we must injure our patients to treat them. In recent years, advances in fiberoptic imaging technology, applied to other surgical specialties, suggested the possibility that cardiac surgery might also be perf...

journal_title：Current opinion in cardiology

authors： Burke RP

更新日期：1999-01-01 00:00:00

abstract：:Venous graft disease is a thromboproliferative process and places a serious limitation on the symptom-free survival of patients after coronary artery bypass grafting. The efficacy of antithrombotics, especially during the first year after surgery, is suggested by an understanding of the four described phases of diseas...

journal_title：Current opinion in cardiology

authors： Schussheim AE,Fuster V

更新日期：1998-11-01 00:00:00